Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Activated charcoal
Drug ID BADD_D00038
Description Activated charcoal, or activated carbon, is an amorphous form of carbon prepared from incomplete combustion of carbonaceous organic matter. It is activated by an oxidizing gas flow at high temperature passed over its surface to make a fine network of pores, producing a material with large surface area and high affinity for various substances. It is used as a gastric decontaminant and emergency medication to treat poisonings following excessive oral ingestion of certain medications or poisons by absorbing most drugs and toxins. However its effects is rendered poor on some compounds including strong acids or bases, methanol and substances with limited absorptive capacity (including iron, lithium, arsenic). It works by binding to the poison in the gastric contents in a reversible fashion thus may be adminstered together with a cathartic to reduce the small intestine transit time. The clinical applications of activated charcoal occured in the early 1800's. While this management for acute poisoning is considered fairly invasive, it is on the World Health Organization's List of Essential Medicines that includes the most important medications needed in a basic health system.
Indications and Usage Used as a antidote to treat poisonings following excessive oral ingestion of certain medications or poisons.
Marketing Status Not Available
ATC Code A07BA01
DrugBank ID DB09278
KEGG ID D03251
MeSH ID D002606
PubChem ID 5462310
TTD Drug ID D06ZVG
NDC Product Code 0574-0521; 0574-0121; 0220-1173; 0220-1168; 0220-1169; 76472-3011; 0220-1177; 68428-287; 0220-1172; 0574-0122; 0220-1200; 0220-1196; 68428-089; 51662-1200; 0220-1176; 0220-1201; 0220-1197; 76472-1139; 0574-0520; 0220-1158; 0395-0527; 68428-039
Synonyms Charcoal | Liqui-Char | Actidose | Actidose-Aqua | Activated Charcoal | Charcoal, Activated | Adsorba | Carbomix | Charbon | CharcoAid | CharcoCaps | Charcodote | Formocarbine | Insta-Char | Kohle-Compretten | Kohle-Hevert | Kohle-Pulvis | Kohle-Tabletten Boxo-Pharm | Ultracarbon | Norit
Chemical Information
Molecular Formula C
CAS Registry Number 1333-86-4
SMILES [C]
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Death08.04.01.001--
Erythema23.03.06.001--Not Available
Hypernatraemia14.05.04.001--
Skin irritation23.03.04.009--Not Available
Obstructive airways disorder22.03.01.011--Not Available
Gastrointestinal obstruction07.13.01.005--Not Available
The 1th Page    1    Total 1 Pages