Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acitretin
Drug ID BADD_D00036
Description An oral retinoid effective in the treatment of psoriasis. It is the major metabolite of etretinate with the advantage of a much shorter half-life when compared with etretinate.
Indications and Usage Zouboulis CC: Retinoids--which dermatological indications will benefit in the near future? Skin Pharmacol Appl Skin Physiol. 2001 Sep-Oct;14(5):303-15.
Marketing Status Prescription; Discontinued
ATC Code D05BB02
DrugBank ID DB00459
KEGG ID D02754
MeSH ID D017255
PubChem ID 5284513
NDC Product Code 42291-088; 0145-0091; 17337-0004; 76055-0001; 71214-0668; 0093-1136; 0093-1135; 58159-058; 42794-081; 42794-080; 0093-1138; 0145-0090; 62147-0145; 42794-083; 42291-086; 71214-0667; 71214-0669; 0378-7020; 0115-1750; 0115-1751; 0115-1752; 71214-0698; 42291-087; 62147-0146; 0378-7023; 17337-0003; 59981-011; 0115-1753
Synonyms Acitretin | Etretin | Isoacitretin | Isoetretin | Ro 10-1670 | Ro 101670 | Ro-10-1670 | Ro101670 | 13-cis-Acitretin | Neotigason | Soriatane | Acitretin, (Z,E,E,E)-Isomer | Ro-13-7652 | Ro137652 | Ro 13-7652 | Ro 137652
Chemical Information
Molecular Formula C21H26O3
CAS Registry Number 55079-83-9
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Not AvailableNot AvailableNot AvailableNot AvailableNot Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Blood albumin decreased13.09.01.001--Not Available
Blood albumin increased13.09.01.002--Not Available
Blood bilirubin increased13.03.01.008--
Blood calcium decreased13.11.01.002--Not Available
Blood calcium increased13.11.01.003--Not Available
Blood chloride decreased13.11.01.004--Not Available
Blood chloride increased13.11.01.005--Not Available
Blood cholesterol increased13.12.01.002--
Blood creatine phosphokinase increased13.04.01.001--
Blood creatinine increased13.13.01.0040.008592%
Blood glucose decreased13.02.02.001--Not Available
Blood glucose increased13.02.02.002--Not Available
Blood iron decreased13.11.01.006--Not Available
Blood iron increased13.11.01.007--Not Available
Blood lactate dehydrogenase increased13.04.02.002--
Blood magnesium decreased13.11.01.008--Not Available
Blood magnesium increased13.11.01.009--Not Available
Blood potassium decreased13.11.01.010--Not Available
Blood potassium increased13.11.01.011--Not Available
Blood sodium decreased13.11.01.012--Not Available
Blood sodium increased13.11.01.013--Not Available
Blood triglycerides increased13.12.03.001--Not Available
Blood urea increased13.13.01.006--Not Available
Blood uric acid increased13.02.04.001--Not Available
Body temperature increased13.15.01.001--Not Available
Bone disorder15.02.04.004--Not Available
Bone pain15.02.01.001--
Bowen's disease23.08.02.004; Available
Bradycardia02.03.02.0020.011456%Not Available
Breast pain21.05.05.003--
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