Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acetylcholine
Drug ID BADD_D00030
Description A neurotransmitter. Acetylcholine in vertebrates is the major transmitter at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system. It is generally not used as an administered drug because it is broken down very rapidly by cholinesterases, but it is useful in some ophthalmological applications.
Indications and Usage Used to obtain miosis of the iris in seconds after delivery of the lens in cataract surgery, in penetrating keratoplasty, iridectomy and other anterior segment surgery where rapid miosis may be required.
Marketing Status approved; investigational
ATC Code S01EB09
DrugBank ID DB03128
KEGG ID D00999
MeSH ID D000109
PubChem ID 187
TTD Drug ID D0Q9HF
NDC Product Code Not Available
UNII N9YNS0M02X
Synonyms Acetylcholine | 2-(Acetyloxy)-N,N,N-trimethylethanaminium | Acetylcholine L-Tartrate | Acetylcholine L Tartrate | L-Tartrate, Acetylcholine | Acetylcholine Perchlorate | Perchlorate, Acetylcholine | Acetylcholine Picrate (1:1) | Acetylcholine Picrate | Acetylcholine Hydroxide | Hydroxide, Acetylcholine | Miochol | Acetilcolina Cusi | Cusi, Acetilcolina | Acetylcholine Bromide | Bromide, Acetylcholine | Bromoacetylcholine | Acetylcholine Chloride | Chloroacetylcholine | Acetylcholine Fluoride | Fluoride, Acetylcholine | Acetylcholine Iodide | Iodide, Acetylcholine | Acetylcholine Sulfate (1:1)
Chemical Information
Molecular Formula C7H16NO2+
CAS Registry Number 51-84-3
SMILES CC(=O)OCC[N+](C)(C)C
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Bradycardia02.03.02.002--Not Available
Corneal oedema06.04.02.001--Not Available
Corneal opacity06.06.03.005--Not Available
Dyspnoea02.11.05.003; 22.02.01.004--
Flushing24.03.01.002; 23.06.05.003; 08.01.03.025--
Hyperhidrosis08.01.03.028; 23.02.03.004--
Hypotension24.06.03.002--
Corneal decompensation06.08.01.003--Not Available
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ADReCS-Target
Drug Name ADR Term Target
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