Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol hydrochloride
Drug ID BADD_D00020
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status Prescription; Discontinued
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D00597
MeSH ID D000070
PubChem ID 441307
TTD Drug ID D0HD9K
NDC Product Code 53746-670; 10135-630; 52932-0719; 65162-670; 51927-2906; 50268-050; 65162-669; 68069-0009; 58159-081; 10135-631; 53746-669
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H29ClN2O4
CAS Registry Number 34381-68-5
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C.Cl
Chemical Structure
ADR Related Proteins Induced by Drug
ADR Term Protein Name UniProt AC TTD Target ID PMID
Adverse drug reactionCytochrome P450 2D6P10635T57392Not Available
ADRs Induced by Drug
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.01.003--
Alopecia23.02.02.001--
Amnesia19.20.01.001; 17.03.02.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.01.006--
Atrioventricular block02.03.01.002--Not Available
Back pain15.03.04.005--
Blood bilirubin increased13.03.01.008--
Blood lactate dehydrogenase increased13.04.02.002--
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Catatonia19.11.01.001--Not Available
Chest pain22.02.08.003; 08.01.08.002; 02.02.02.011--Not Available
Chromaturia20.02.01.002--
Colitis ischaemic24.04.08.012; 07.08.01.004--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.01.02.004; 24.06.02.007; 17.02.05.003--
Dry eye06.08.02.001--
Dyspepsia07.01.02.001--
Dyspnoea22.02.01.004; 02.01.03.002--
Dysuria20.02.02.002--
The 1th Page    1 2 3    Next   Last    Total 3 Pages