Adverse Drug Reaction Classification System

Pharmaceutical Information
Drug Name Acebutolol hydrochloride
Drug ID BADD_D00020
Description A cardioselective beta-adrenergic antagonist with little effect on the bronchial receptors. The drug has stabilizing and quinidine-like effects on cardiac rhythm as well as weak inherent sympathomimetic action.
Indications and Usage For the management of hypertension and ventricular premature beats in adults.
Marketing Status approved; investigational
ATC Code C07AB04
DrugBank ID DB01193
KEGG ID D00597
MeSH ID D000070
PubChem ID 441307
TTD Drug ID D0HD9K
NDC Product Code 52932-0719; 65162-670; 58159-081; 65162-669; 62559-255; 51407-666; 42291-010; 62559-256; 50268-050; 53746-669; 51927-2906; 68069-0009; 53746-670; 51407-667
UNII B025Y34C54
Synonyms Acebutolol | Acetobutolol | Acebutolol Hydrochloride | M&B-17803 A | M&B 17803 A | M&B17803 A | M & B 17803A | Neptal | Prent | Rhotral | Sectral | Monitan | Apo-Acebutolol | Apo Acebutolol | ApoAcebutolol | Novo-Acebutolol | Novo Acebutolol | NovoAcebutolol
Chemical Information
Molecular Formula C18H29ClN2O4
CAS Registry Number 34381-68-5
SMILES CCCC(=O)NC1=CC(=C(C=C1)OCC(CNC(C)C)O)C(=O)C.Cl
Chemical Structure
ADRs Induced by Drug
*The priority for ADR severity classification is based on FAERS assessment, followed by the most severe level in CTCAE rating. If neither is available, it will be displayed as 'Not available'.
**The 'Not Available' level is hidden by default and can be restored by clicking on the legend twice..
ADR Term ADReCS ID ADR Frequency (FAERS) ADR Severity Grade (FAERS) ADR Severity Grade (CTCAE)
Abdominal pain07.01.05.002--
Abnormal dreams19.02.03.001; 17.15.02.001--Not Available
Agranulocytosis01.02.03.001--Not Available
Alanine aminotransferase increased13.03.04.005--
Alopecia23.02.02.001--
Amnesia19.20.01.001; 17.03.02.001--
Anxiety19.06.02.002--
Arthralgia15.01.02.001--
Aspartate aminotransferase increased13.03.04.011--
Atrioventricular block02.03.01.002--Not Available
Back pain15.03.04.005--
Blood bilirubin increased13.03.04.018--
Blood lactate dehydrogenase increased13.04.02.002--
Bradycardia02.03.02.002--Not Available
Cardiac failure02.05.01.001--
Catatonia19.11.01.001--Not Available
Chest pain22.12.02.003; 08.01.08.002; 02.02.02.011--Not Available
Chromaturia20.02.01.002--
Colitis ischaemic24.04.08.012; 07.08.01.004--Not Available
Conjunctivitis06.04.01.002; 11.01.06.012--
Constipation07.02.02.001--
Cough22.02.03.001--
Depressed level of consciousness17.02.04.002--
Depression19.15.01.001--
Diarrhoea07.02.01.001--
Dizziness02.11.04.006; 24.06.02.007; 17.02.05.003--
Dry eye06.08.02.001--
Dyspepsia07.01.02.001--
Dyspnoea02.11.05.003; 22.02.01.004--
Dysuria20.02.02.002--
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