Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Oxidative stress
ADR ID BADD_A10589
ADR Hierarchy
14      Metabolism and nutrition disorders
14.11      Metabolism disorders NEC
14.11.01      Metabolic disorders NEC
14.11.01.054      Oxidative stress
Description A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi). [MeSH]
MedDRA Code 10080562
MeSH ID D018384
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Oxidative stress | Oxidative Stress | Oxidative Stresses | Stresses, Oxidative | Stress, Oxidative
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01418Methotrexate0.000398%
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