Adverse Drug Reaction Classification System

ADR Ontology
ADR Term EGFR gene mutation
ADR ID BADD_A09140
ADR Hierarchy
08      General disorders and administration site conditions
08.01      General system disorders NEC
08.01.10      Acquired gene mutations and other alterations
08.01.10.004      EGFR gene mutation
Description Not Available
MedDRA Code 10071975
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
EGFR gene mutation | Epidermal growth factor receptor gene mutation | EGFR exon 19 deletion | Point mutation in exon 21 (L858R)
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00047Afatinib0.008259%
BADD_D01008Gefitinib0.000417%
BADD_D01629Osimertinib0.000799%
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