Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Propofol infusion syndrome
ADR ID BADD_A08670
ADR Hierarchy
02      Cardiac disorders
02.05      Heart failures
02.05.01      Heart failures NEC
02.05.01.014      Propofol infusion syndrome
14      Metabolism and nutrition disorders
14.01      Acid-base disorders
14.01.01      Metabolic acidoses (excl diabetic acidoses)
14.01.01.015      Propofol infusion syndrome
20      Renal and urinary disorders
20.01      Renal disorders (excl nephropathies)
20.01.03      Renal failure and impairment
20.01.03.023      Propofol infusion syndrome
Description Rare and often fatal drug complication which affects patients undergoing long-term treatment with high doses of PROPOFOL. It is characterized by METABOLIC ACIDOSIS; HYPERLIPIDEMIA; RHABDOMYOLYSIS; cardiovascular CIRCULATORY COLLAPSE; CARDIAC FAILURE; and KIDNEY FAILURE. [MeSH]
MedDRA Code 10063181
MeSH ID D000072736
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Propofol infusion syndrome | Propofol syndrome | Propofol Infusion Syndrome | Propofol Infusion Syndromes | Propofol Syndrome | Propofol Syndromes | Propofol-Related Infusion Syndrome | Propofol Related Infusion Syndrome | Propofol-Related Infusion Syndromes
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01864Propofol0.009896%
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