Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Acantholysis
ADR ID BADD_A08382
ADR Hierarchy
23      Skin and subcutaneous tissue disorders
23.03      Epidermal and dermal conditions
23.03.03      Dermal and epidermal conditions NEC
23.03.03.062      Acantholysis
Description Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE. [MeSH]
MedDRA Code 10058820
MeSH ID D000051
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Acantholysis | Acantholyses
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D02344Vemurafenib0.000358%
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