Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bartter's syndrome
ADR ID BADD_A08000
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.06      Renal and urinary tract disorders congenital
03.06.02      Renal and urinary tract disorders congenital NEC
03.06.02.004      Bartter's syndrome
14      Metabolism and nutrition disorders
14.05      Electrolyte and fluid balance conditions
14.05.01      Electrolyte imbalance NEC
14.05.01.007      Bartter's syndrome
20      Renal and urinary disorders
20.05      Nephropathies
20.05.03      Nephropathies and tubular disorders NEC
20.05.03.015      Bartter's syndrome
Description A group of disorders caused by defective salt reabsorption in the ascending LOOP OF HENLE. It is characterized by severe salt-wasting, HYPOKALEMIA; HYPERCALCIURIA; metabolic ALKALOSIS, and hyper-reninemic HYPERALDOSTERONISM without HYPERTENSION. There are several subtypes including ones due to mutations in the renal specific SODIUM-POTASSIUM-CHLORIDE SYMPORTERS. [MeSH]
MedDRA Code 10050839
MeSH ID D001477
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Juxtaglomerular cell hyperplasia | Bartter's syndrome | Bartter Syndrome | Syndrome, Bartter | Juxtaglomerular Hyperplasia with Secondary Aldosteronism | Bartter's Disease | Bartters Disease | Bartter's Syndrome | Bartters Syndrome | Syndrome, Bartter's | Aldosteronism with Hyperplasia of the Adrenal Cortex | Bartter Disease
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00979Furosemide0.000063%
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