Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Visceral leishmaniasis
ADR ID BADD_A07822
ADR Hierarchy
11      Infections and infestations
11.06      Protozoal infectious disorders
11.06.08      Leishmania infections
11.06.08.002      Visceral leishmaniasis
Description A chronic disease caused by LEISHMANIA DONOVANI and transmitted by the bite of several sandflies of the genera Phlebotomus and Lutzomyia. It is commonly characterized by fever, chills, vomiting, anemia, hepatosplenomegaly, leukopenia, hypergammaglobulinemia, emaciation, and an earth-gray color of the skin. The disease is classified into three main types according to geographic distribution: Indian, Mediterranean (or infantile), and African. [MeSH]
MedDRA Code 10047505
MeSH ID D007898; D007898; D007898
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Kala-azar | L. infantum | L.donovani | Leishmania donovani infection | Leishmaniasis visceral (kala-azar) | Post kala-azar dermal leishmaniasis | Visceral leishmaniasis | Visceral leishmaniasis Mediterranean | Dumdum fever | Leishmaniasis, Visceral | Visceral Leishmaniasis | Kala-Azar | Kala Azar | Black Fever | Fever, Black
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01418Methotrexate0.001960%
BADD_D01507Mycophenolate mofetil0.001308%
BADD_D02464Fingolimod0.001158%
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