Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Thalassaemia
ADR ID BADD_A07749
ADR Hierarchy
01      Blood and lymphatic system disorders
01.04      Haemoglobinopathies
01.04.03      Thalassaemic disorders
01.04.03.001      Thalassaemia
03      Congenital, familial and genetic disorders
03.15      Blood and lymphatic system disorders congenital
03.15.03      Haemoglobinopathies congenital
03.15.03.002      Thalassaemia
Description A group of hereditary hemolytic anemias in which there is decreased synthesis of one or more hemoglobin polypeptide chains. There are several genetic types with clinical pictures ranging from barely detectable hematologic abnormality to severe and fatal anemia. [MeSH]
MedDRA Code 10043388
MeSH ID D013789
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Mediterranean anaemia (with other haemoglobinopathy) | Thalassaemia | Thalassaemia NOS | Thalassaemias | Thalassemias | Mediterranean anemia (with other hemoglobinopathy) | Thalassemia | Non-transfusion dependent thalassaemia | Non-transfusion dependent thalassemia
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Tyrosine-protein kinase ABL1P00519T63505
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00511Clozapine--
BADD_D01322Losartan--
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