Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bulbar palsy
ADR ID BADD_A07010
ADR Hierarchy
17      Nervous system disorders
17.04      Cranial nerve disorders (excl neoplasms)
17.04.10      Mixed cranial nerve disorders
17.04.10.001      Bulbar palsy
Description A motor neuron disease marked by progressive weakness of the muscles innervated by cranial nerves of the lower brain stem. Clinical manifestations include dysarthria, dysphagia, facial weakness, tongue weakness, and fasciculations of the tongue and facial muscles. The adult form of the disease is marked initially by bulbar weakness which progresses to involve motor neurons throughout the neuroaxis. Eventually this condition may become indistinguishable from AMYOTROPHIC LATERAL SCLEROSIS. Fazio-Londe syndrome is an inherited form of this illness which occurs in children and young adults. (Adams et al., Principles of Neurology, 6th ed, p1091; Brain 1992 Dec;115(Pt 6):1889-1900) [MeSH]
MedDRA Code 10006542
MeSH ID D010244
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bulbar palsy | Bulbar paralysis | Paralysis bulbar | Bulbar Palsy, Progressive | Bulbar Palsies, Progressive | Palsies, Progressive Bulbar | Palsy, Progressive Bulbar | Progressive Bulbar Palsies | Progressive Bulbar Palsy | Bulbar Palsy | Bulbar Palsies | Palsies, Bulbar | Palsy, Bulbar | Paralysis, Bulbar | Bulbar Paralyses | Bulbar Paralysis | Childhood Progressive Bulbar Palsy | Bulbar Palsy, Progressive, Of Childhood | Progressive Bulbar Palsy of Childhood | Fazio-Londe Syndrome | Fazio Londe Syndrome | Fazio-Londe Disease | Fazio Londe Disease
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01633Oxaliplatin0.000224%
BADD_D02464Fingolimod0.000241%
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