Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Traumatic lung injury
ADR ID BADD_A06562
ADR Hierarchy
12      Injury, poisoning and procedural complications
12.01      Injuries NEC
12.01.03      Chest and lung injuries NEC
12.01.03.003      Traumatic lung injury
22      Respiratory, thoracic and mediastinal disorders
22.01      Lower respiratory tract disorders (excl obstruction and infection)
22.01.02      Parenchymal lung disorders NEC
22.01.02.013      Traumatic lung injury
Description Damage to any compartment of the lung caused by physical, chemical, or biological agents which characteristically elicit inflammatory reaction. These inflammatory reactions can either be acute and dominated by NEUTROPHILS, or chronic and dominated by LYMPHOCYTES and MACROPHAGES. [MeSH]
MedDRA Code 10069363
MeSH ID D055370
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Laceration of lung with open wound into thorax | Laceration of lung without open wound into thorax | Lung injury NOS | Lung injury, with open wound into thorax | Lung injury, without mention of open wound into thorax | Unspecified injury of lung with open wound into thorax | Unspecified injury of lung without open wound into thorax | Lung injury | Traumatic lung injury | Lung Injury | Injuries, Lung | Injury, Lung | Pulmonary Injury | Injuries, Pulmonary | Injury, Pulmonary | Pulmonary Injuries | Lung Injuries | Chronic Lung Injury | Chronic Lung Injuries | Lung Injuries, Chronic | Lung Injury, Chronic
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Pulmonary surfactant-associated protein DP35247T35862
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam0.000084%
BADD_D00115Amiodarone0.002381%
BADD_D00195Azathioprine0.003590%
BADD_D00284Bortezomib0.000139%
BADD_D00285Bosentan0.000175%
BADD_D00349Capecitabine0.000799%
BADD_D00364Carboplatin0.000139%
BADD_D00511Clozapine0.005605%
BADD_D00560Cytarabine0.001598%
BADD_D00564Dabigatran etexilate0.001055%
BADD_D00686Diphenhydramine0.000132%
BADD_D00723Doxorubicin0.000533%
BADD_D01010Gemcitabine hydrochloride--
BADD_D01096Hydromorphone0.000826%
BADD_D01253Lenalidomide--
BADD_D01418Methotrexate0.005600%
BADD_D01633Oxaliplatin0.000208%
BADD_D01942Riluzole0.002614%
BADD_D02026Simvastatin0.000077%
BADD_D02033Sodium aurothiomalate--
BADD_D02170Testosterone0.000594%
BADD_D02414Mesalazine0.009347%
BADD_D02419Rosiglitazone0.001001%
BADD_D02470Nintedanib0.000533%
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