Adverse Drug Reaction Classification System

ADR Ontology
ADR Term AIDS dementia complex
ADR ID BADD_A06288
ADR Hierarchy
10      Immune system disorders
10.03      Immunodeficiency syndromes
10.03.03      Acquired immunodeficiency syndromes
10.03.03.005      AIDS dementia complex
11      Infections and infestations
11.05      Viral infectious disorders
11.05.17      Retroviral infections
11.05.17.008      AIDS dementia complex
17      Nervous system disorders
17.03      Mental impairment disorders
17.03.01      Dementia (excl Alzheimer's type)
17.03.01.005      AIDS dementia complex
19      Psychiatric disorders
19.20      Dementia and amnestic conditions
19.20.02      Dementia NEC
19.20.02.004      AIDS dementia complex
Description A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40) [MeSH]
MedDRA Code 10065040
MeSH ID D015526; D015526; D015526
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
AIDS dementia | AIDS-dementia complex | AIDS-related dementia | Dementia due to HIV disease | HIV-related dementia | AIDS encephalopathy | AIDS dementia complex | HIV encephalopathy | AIDS Dementia Complex | Complex, AIDS Dementia | Dementia Complex, AIDS | HIV-Associated Cognitive Motor Complex | HIV Associated Cognitive Motor Complex | Dementia Complex, Acquired Immune Deficiency Syndrome | Acquired-Immune Deficiency Syndrome Dementia Complex | AIDS-Related Dementia Complex | AIDS Related Dementia Complex | HIV Dementia | Dementia, HIV | Dementias, HIV | HIV Dementias | Dementia Complex, AIDS-Related | Complex, AIDS-Related Dementia | Dementia Complex, AIDS Related | HIV-1-Associated Cognitive Motor Complex | HIV 1 Associated Cognitive Motor Complex | HIV-1 Cognitive and Motor Complex | HIV 1 Cognitive and Motor Complex | HIV Encephalopathy | Encephalopathies, HIV | HIV Encephalopathies | Encephalopathy, AIDS | Encephalopathy, HIV | AIDS Encephalopathy | AIDS Encephalopathies | Encephalopathies, AIDS
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00008Abacavir--
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