Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Sex hormone binding globulin
ADR ID BADD_A05685
ADR Hierarchy
13      Investigations
13.10      Endocrine investigations (incl sex hormones)
13.10.05      Reproductive hormone analyses
13.10.05.016      Sex hormone binding globulin
Description A glycoprotein migrating as a beta-globulin. Its molecular weight, 52,000 or 95,000-115,000, indicates that it exists as a dimer. The protein binds testosterone, dihydrotestosterone, and estradiol in the plasma. Sex hormone-binding protein has the same amino acid sequence as ANDROGEN-BINDING PROTEIN. They differ by their sites of synthesis and post-translational oligosaccharide modifications. [MeSH]
MedDRA Code 10059654
MeSH ID D012738
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Sex hormone binding globulin | Sex Hormone-Binding Globulin | Globulin, Sex Hormone-Binding | Hormone-Binding Globulin, Sex | Sex Hormone Binding Globulin | Testosterone-Estradiol Binding Globulin | Binding Globulin, Testosterone-Estradiol | Globulin, Testosterone-Estradiol Binding | Testosterone Estradiol Binding Globulin | Sex Steroid-Binding Protein | Sex Steroid Binding Protein | Steroid-Binding Protein, Sex
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00576Danazol--
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