| ADR Ontology |
| ADR Term |
Congenital aplastic anaemia |
| ADR ID |
BADD_A05226 |
| ADR Hierarchy |
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| Description |
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004) [MeSH] |
| MedDRA Code |
10053138 |
| MeSH ID |
D005199; D029503
|
|
ADR Severity Grade (FAERS)
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|
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ADR Severity Grade (CTCAE)
|
Not Available
|
| Synonym |
| Fanconi's anaemia | Congenital aplastic anaemia | Congenital aplastic anemia | Fanconi's anemia | Diamond-Blackfan anaemia | Diamond-Blackfan anemia | Inherited bone marrow failure syndrome | Fanconi Anemia | Anemias, Fanconi | Fanconi Anemias | Fanconi's Anemia | Anemia, Fanconi's | Fanconi Pancytopenia | Fanconi Panmyelopathy | Anemia, Fanconi | Fanconi Hypoplastic Anemia |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
|
| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D00594 | Deferasirox | 0.001521% | | | BADD_D00696 | Divalproex sodium | - | - |
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