Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Bone marrow toxicity
ADR ID BADD_A05061
ADR Hierarchy
01      Blood and lymphatic system disorders
01.03      Anaemias nonhaemolytic and marrow depression
01.03.03      Marrow depression and hypoplastic anaemias
01.03.03.004      Bone marrow toxicity
12      Injury, poisoning and procedural complications
12.03      Exposures, chemical injuries and poisoning
12.03.01      Poisoning and toxicity
12.03.01.006      Bone marrow toxicity
Description Not Available
MedDRA Code 10051779
MeSH ID Not Available
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Bone marrow toxicity
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Cytosolic 5'-nucleotidase 1AQ9BXI3Not Available
Dihydropyrimidine dehydrogenase [NADP(+)]Q12882T75890
N-alpha-acetyltransferase 20P61599Not Available
Purine nucleoside phosphorylaseP00491T78198
Thiopurine S-methyltransferaseP51580Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00085Alprazolam--
BADD_D00176Atazanavir--
BADD_D00195Azathioprine--
BADD_D00280Bleomycin--
BADD_D00285Bosentan--
BADD_D00349Capecitabine--
BADD_D00356Carbamazepine--
BADD_D00364Carboplatin--
BADD_D00474Cisplatin--
BADD_D00504Clopidogrel--
BADD_D00643Diamminedichloroplatinum--
BADD_D00913Flucytosine--
BADD_D00931Fluorouracil--
BADD_D01009Gemcitabine--
BADD_D01133Ifosfamide--
BADD_D01242Lamivudine--
BADD_D01253Lenalidomide--
BADD_D01295Linezolid--
BADD_D01313Lomustine--
BADD_D01392Mercaptopurine--
BADD_D01393Meropenem--
BADD_D01418Methotrexate--
BADD_D01449Metronidazole--
BADD_D01478Mitomycin--
BADD_D01507Mycophenolate mofetil--
BADD_D01601Olaparib--
BADD_D01609Omacetaxine mepesuccinate--
BADD_D01654Palbociclib--
BADD_D01933Ribavirin--
BADD_D02075Strontium chloride sr-89--
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