| ADR Ontology |
| ADR Term |
Turner's syndrome |
| ADR ID |
BADD_A04404 |
| ADR Hierarchy |
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| Description |
A syndrome of defective gonadal development in phenotypic females associated with the karyotype 45,X (or 45,XO). Patients generally are of short stature with undifferentiated GONADS (streak gonads), SEXUAL INFANTILISM, HYPOGONADISM, webbing of the neck, cubitus valgus, elevated GONADOTROPINS, decreased ESTRADIOL level in blood, and CONGENITAL HEART DEFECTS. NOONAN SYNDROME (also called Pseudo-Turner Syndrome and Male Turner Syndrome) resembles this disorder; however, it occurs in males and females with a normal karyotype and is inherited as an autosomal dominant. | This syndrome that was originally observed by Ullrich, and designated as identical to TURNER SYNDROME, related the webbing of the neck, loose skin and other anomalies of the syndrome to accumulation of fluid in the embryo starting at the head and dispersing to the extremities (as observed by Bonnevie in mice). Commonly observed at birth in Turner Syndrome and NOONAN SYNDROME; EDEMA of the extremities usually recedes by one year and is an early sign of Turner syndrome, especially in female neonates. [MeSH] |
| MedDRA Code |
10045181 |
| MeSH ID |
D014424
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ADR Severity Grade (FAERS)
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Not Available
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Bonnevie-Ullrich syndrome | Turner's syndrome | XO genotype | XXO genotype | 45,X genotype | 45,XO genotype | Turner Syndrome | Ullrich-Turner Syndrome | Syndrome, Ullrich-Turner | Ullrich Turner Syndrome | Turner's Syndrome | Turners Syndrome | Gonadal Dysgenesis, 45,X | Gonadal Dysgenesis, XO | XO Gonadal Dysgenesis | Monosomy X | Bonnevie-Ullrich Syndrome | Bonnevie Ullrich Syndrome | Status Bonnevie-Ullrich | Status Bonnevie Ullrich |
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| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D01366 | Medroxyprogesterone acetate | - | - |
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