| ADR Ontology |
| ADR Term |
Spina bifida |
| ADR ID |
BADD_A04119 |
| ADR Hierarchy |
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| Description |
Congenital defects of closure of one or more vertebral arches, which may be associated with malformations of the spinal cord, nerve roots, congenital fibrous bands, lipomas, and congenital cysts. These malformations range from mild (e.g., SPINA BIFIDA OCCULTA) to severe, including rachischisis where there is complete failure of neural tube and spinal cord fusion, resulting in exposure of the spinal cord at the surface. Spinal dysraphism includes all forms of spina bifida. The open form is called SPINA BIFIDA CYSTICA and the closed form is SPINA BIFIDA OCCULTA. (From Joynt, Clinical Neurology, 1992, Ch55, p34) [MeSH] |
| MedDRA Code |
10041524 |
| MeSH ID |
D016135; D016135; D016137
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Hydrocele, spinal | Open spina bifida | Spina bifida | Spina bifida with hydrocephalus | Spina bifida with hydrocephalus, cervical region | Spina bifida with hydrocephalus, dorsal (thoracic) region | Spina bifida with hydrocephalus, lumbar region | Spina bifida with hydrocephalus, unspecified region | Spina bifida without mention of hydrocephalus | Spina bifida, without mention of hydrocephalus, cervical region | Spina bifida, without mention of hydrocephalus, dorsal (thoracic) region | Spina bifida, without mention of hydrocephalus, lumbar region | Spina bifida, without mention of hydrocephalus, unspecified region | With hydrocephalus, spina bifida, cervical region | With hydrocephalus, spina bifida, dorsal (thoracic) region | With hydrocephalus, spina bifida, lumbar region | With hydrocephalus, spina bifida, unspecified region | Spinal Dysraphism | Dysraphism, Spinal | Dysraphisms, Spinal | Spinal Dysraphisms | Open Spine | Open Spines | Spine, Open | Schistorrhachis | Cleft Spine | Cleft Spines | Spine, Cleft | Spinal Dysraphia | Dysraphia, Spinal | Spinal Dysraphias | Spina Bifida | Bifida, Spina | Spina Bifidas | Status Dysraphicus | Dysraphicus, Status | Rachischisis | Rachischises |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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