| ADR Ontology |
| ADR Term |
Herpes simplex encephalitis |
| ADR ID |
BADD_A02061 |
| ADR Hierarchy |
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| Description |
An acute (or rarely chronic) inflammatory process of the brain caused by SIMPLEXVIRUS infections which may be fatal. The majority of infections are caused by human herpesvirus 1 (HERPESVIRUS 1, HUMAN) and less often by human herpesvirus 2 (HERPESVIRUS 2, HUMAN). Clinical manifestations include FEVER; HEADACHE; SEIZURES; HALLUCINATIONS; behavioral alterations; APHASIA; hemiparesis; and COMA. Pathologically, the condition is marked by a hemorrhagic necrosis involving the medial and inferior TEMPORAL LOBE and orbital regions of the FRONTAL LOBE. (From Adams et al., Principles of Neurology, 6th ed, pp751-4) [MeSH] |
| MedDRA Code |
10019953 |
| MeSH ID |
D020803
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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Not Available
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| Synonym |
| Herpes simplex encephalitis | Herpes simplex encephalomyelitis | Encephalitis, Herpes Simplex | Encephalitides, Herpes Simplex | Herpes Simplex Encephalitides | Herpes Encephalitis | Encephalitis, Herpes | Herpetic Encephalitis | Encephalitides, Herpetic | Encephalitis, Herpetic | Herpetic Encephalitides | Herpes Simplex Encephalitis | Meningoencephalitis, Herpes Simplex Virus | Herpetic Meningoencephalitis | Herpetic Meningoencephalitides | Meningoencephalitides, Herpetic | Meningoencephalitis, Herpetic | Herpes Simplex Meningoencephalitis | Herpes Simplex Meningoencephalitides | Meningoencephalitides, Herpes Simplex | Meningoencephalitis, Herpes Simplex | Herpetic Acute Necrotizing Encephalitis | Acute Necrotizing Encephalitis, Herpetic |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
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