Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Encephalocele
ADR ID BADD_A01459
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.10      Neurological disorders congenital
03.10.02      Central nervous system disorders congenital NEC
03.10.02.001      Encephalocele
17      Nervous system disorders
17.19      Congenital and peripartum neurological conditions
17.19.01      Congenital and hereditary central nervous system disorders NEC
17.19.01.005      Encephalocele
Description Brain tissue herniation through a congenital or acquired defect in the skull. The majority of congenital encephaloceles occur in the occipital or frontal regions. Clinical features include a protuberant mass that may be pulsatile. The quantity and location of protruding neural tissue determines the type and degree of neurologic deficit. Visual defects, psychomotor developmental delay, and persistent motor deficits frequently occur. [MeSH]
MedDRA Code 10014617
MeSH ID D004677
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Encephalocele | Encephalomeningocele | Encephalocystocele | Encephaloceles | Cephalocele | Cephaloceles | Cranial Meningoencephalocele | Cranial Meningoencephaloceles | Meningoencephalocele, Cranial | Meningoencephaloceles, Cranial | Cranium Bifidum | Bifidum, Cranium | Bifidums, Cranium | Cranium Bifidums | Hernia, Cerebral | Cerebral Hernia | Cerebral Hernias | Hernias, Cerebral | Bifid Cranium | Bifid Craniums | Cranium, Bifid | Craniums, Bifid | Craniocele | Cranioceles | Frontal Encephalocele | Encephaloceles, Frontal | Frontal Encephaloceles | Encephalocele, Frontal | Cerebellar Herniation | Cerebellar Herniations | Herniation, Cerebellar | Herniations, Cerebellar | Tonsillar Hernia | Hernia, Tonsillar | Hernias, Tonsillar | Tonsillar Hernias | Tonsillar Herniation | Herniation, Tonsillar | Herniations, Tonsillar | Tonsillar Herniations | Cerebellar Hernia | Cerebellar Hernias | Hernia, Cerebellar | Hernias, Cerebellar | Acquired Encephalocele | Acquired Encephaloceles | Encephaloceles, Acquired | Encephalocele, Acquired | Encephalocele, Sincipital | Encephaloceles, Sincipital | Sincipital Encephaloceles | Sincipital Encephalocele | Occipital Encephalocele | Encephaloceles, Occipital | Occipital Encephaloceles | Notoencephalocele | Notoencephaloceles | Encephalocele, Occipital
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00151Apixaban0.000104%
BADD_D00195Azathioprine0.000375%
BADD_D00475Citalopram0.000022%
BADD_D00809Escitalopram0.000037%
BADD_D00871Felbamate--
BADD_D00952Folic acid0.000368%
BADD_D01217Itraconazole--
BADD_D01243Lamotrigine0.000134%
BADD_D01508Mycophenolic acid0.000453%
BADD_D01599Olanzapine0.000282%
The 1th Page    1    Total 1 Pages