Adverse Drug Reaction Classification System

         

ADR Ontology
ADR Term Congenital megacolon
ADR ID BADD_A01037
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.04      Gastrointestinal tract disorders congenital
03.04.04      Intestinal disorders congenital
03.04.04.002      Congenital megacolon
07      Gastrointestinal disorders
07.02      Gastrointestinal motility and defaecation conditions
07.02.05      Non-mechanical ileus
07.02.05.005      Congenital megacolon
Description Congenital MEGACOLON resulting from the absence of ganglion cells (aganglionosis) in a distal segment of the LARGE INTESTINE. The aganglionic segment is permanently contracted thus causing dilatation proximal to it. In most cases, the aganglionic segment is within the RECTUM and SIGMOID COLON. [MeSH]
MedDRA Code 10010539
MeSH ID D006627
ADR Severity Grade (FAERS) Not Available
ADR Severity Grade (CTCAE) Not Available
Synonym
Aganglionic megacolon | Congenital megacolon | Hirschsprung's disease | Hirschsprung's disease and other congenital functional disorders of colon | Megacolon congenital | Pelvirectal achalasia | Aganglionosis | Hirschsprung Disease | Disease, Hirschsprung | Megacolon, Congenital | Hirschsprung's Disease | Disease, Hirschsprung's | Hirschsprungs Disease | Megacolon, Aganglionic | Aganglionic Megacolon | Congenital Megacolon | Aganglionosis, Rectosigmoid Colon | Rectosigmoid Colon Aganglionosis | Rectosigmoid Aganglionosis | Aganglionosis, Rectosigmoid | Congenital Intestinal Aganglionosis | Aganglionosis, Colonic | Colonic Aganglionosis | Total Colonic Aganglionosis | Aganglionosis, Total Colonic
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01366Medroxyprogesterone acetate--
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