Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Cerebral palsy
ADR ID BADD_A00847
ADR Hierarchy
03      Congenital, familial and genetic disorders
03.10      Neurological disorders congenital
03.10.03      Cerebral disorders congenital
03.10.03.002      Cerebral palsy
17      Nervous system disorders
17.19      Congenital and peripartum neurological conditions
17.19.03      Congenital and peripartum cerebral disorders
17.19.03.002      Cerebral palsy
18      Pregnancy, puerperium and perinatal conditions
18.04      Neonatal and perinatal conditions
18.04.04      Neonatal neurological system disorders NEC
18.04.04.004      Cerebral palsy
Description A heterogeneous group of nonprogressive motor disorders caused by chronic brain injuries that originate in the prenatal period, perinatal period, or first few years of life. The four major subtypes are spastic, athetoid, ataxic, and mixed cerebral palsy, with spastic forms being the most common. The motor disorder may range from difficulties with fine motor control to severe spasticity (see MUSCLE SPASTICITY) in all limbs. Spastic diplegia (Little disease) is the most common subtype, and is characterized by spasticity that is more prominent in the legs than in the arms. Pathologically, this condition may be associated with LEUKOMALACIA, PERIVENTRICULAR. (From Dev Med Child Neurol 1998 Aug;40(8):520-7) [MeSH]
MedDRA Code 10008129
MeSH ID D002547; D002547; D002547; D002547; D006429
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE) Not Available
Synonym
Cerebral palsy | Congenital spasticity | Diplegic infantile cerebral palsy | Hemiplegic infantile cerebral palsy | Infantile cerebral palsy | Infantile cerebral palsy, diplegic | Infantile cerebral palsy, hemiplegic | Infantile cerebral palsy, monoplegic | Infantile cerebral palsy, quadriplegic | Infantile cerebral palsy, unspecified | Infantile hemiplegia | Monoplegic infantile cerebral palsy | Other specified infantile cerebral palsy | Palsy cerebral | Paralysis spastic congenital | Quadriplegic infantile cerebral palsy | Spastic palsy (infantile) | Spasticity congenital | Athetoid cerebral palsy | Cerebral Palsy | CP (Cerebral Palsy) | Cerebral Palsy, Dystonic-Rigid | Cerebral Palsies, Dystonic-Rigid | Cerebral Palsy, Dystonic Rigid | Dystonic-Rigid Cerebral Palsies | Dystonic-Rigid Cerebral Palsy | Cerebral Palsy, Mixed | Mixed Cerebral Palsies | Mixed Cerebral Palsy | Cerebral Palsy, Monoplegic, Infantile | Monoplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Monoplegic | Cerebral Palsy, Quadriplegic, Infantile | Quadriplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Quadriplegic | Cerebral Palsy, Rolandic Type | Rolandic Type Cerebral Palsy | Cerebral Palsy, Congenital | Congenital Cerebral Palsy | Little Disease | Little's Disease | Spastic Diplegia | Diplegias, Spastic | Spastic Diplegias | Diplegia, Spastic | Monoplegic Cerebral Palsy | Cerebral Palsies, Monoplegic | Cerebral Palsy, Monoplegic | Monoplegic Cerebral Palsies | Cerebral Palsy, Athetoid | Athetoid Cerebral Palsy | Cerebral Palsies, Athetoid | Cerebral Palsy, Dyskinetic | Cerebral Palsies, Dyskinetic | Dyskinetic Cerebral Palsy | Cerebral Palsy, Atonic | Atonic Cerebral Palsy | Cerebral Palsy, Hypotonic | Hypotonic Cerebral Palsies | Hypotonic Cerebral Palsy | Cerebral Palsy, Diplegic, Infantile | Diplegic Infantile Cerebral Palsy | Infantile Cerebral Palsy, Diplegic | Cerebral Palsy, Spastic | Spastic Cerebral Palsies | Spastic Cerebral Palsy
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00356Carbamazepine0.001263%
BADD_D00684Dinoprostone0.000170%
BADD_D00804Erythromycin0.004365%
BADD_D00809Escitalopram0.000095%
BADD_D00932Fluoxetine0.000182%
BADD_D01265Levetiracetam0.000381%
BADD_D01366Medroxyprogesterone acetate0.000511%
BADD_D01477Misoprostol0.002826%
BADD_D01617Ondansetron0.000150%
BADD_D01679Paroxetine0.000280%
BADD_D01752Phenobarbital0.001490%
BADD_D01801Poractant alfa--
BADD_D01954Rivaroxaban0.000357%
BADD_D02010Sertraline0.000063%
BADD_D02105Tacrolimus0.002839%
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